Heading for the Mexico border pursued by Gonzalez, the Geckos encounter former minister Jacob Fuller and his family, whom they take hostage by commandeering the Fullers' RV. In this supernatural crime series, Seth Gecko and his violent, unpredictable brother, Richard 'Richie' Gecko, are wanted by the FBI and Texas Ranger Freddie Gonzalez after a bank robbery left several people, including policemen and Gonzalez's mentor Texas Ranger Earl McGraw, dead. While the series was never officially announced as cancelled, Deadline Hollywood reported that the actors were released from their contracts on October 31. The third season aired from September 6 to November 1, 2016. It was produced by FactoryMade Ventures in association with Miramax and executive produced by Rodriguez. Outside the United States and Latin America, the series is marketed as a Netflix original but was removed in November 2022.

The series premiered on March 11, 2014, on Rodriguez's newly launched El Rey Network.

The series also references the Popol Vuh, drawing on its rich, mythological history and, in particular, on the legend of the Hero Twins Hunahpú and Xbalanqué to add greater depth to the backstories and to fully flesh out the characters of the show's protagonists, the Gecko Brothers, Seth and Richie.

The series adds to the tone of the film, with new characters and backstories, while expanding the snake creatures' Mesoamerican mythology. It forms part of the franchise of film, direct-to-video, and comics of From Dusk till Dawn, expanding on the chronicles of the Gecko Brothers, Seth and Richie The Fuller family and Santanico Pandemonium. From Dusk till Dawn: The Series is an American horror television series developed by Robert Rodriguez.

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